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Titolo A LONGITUDINAL STUDY OF NUTRITIONAL AND INFLAMMATORY STATUS IN PATIENTS ON DIALYSIS
Autore Anastasia Markaki1,2, Kalliopi Gkouskou1,3, Emmanouel Ganotakis4, Andrew Margioris5, Eugene Daphnis2 - 1Department of Nutrition and Dietetics, Technological Education Institute of Crete, Sitia, Greece - 2Department of Nephrology, University Hospital of Heraklion, Crete, Greece - 3Institute of Molecular Biology and Biotechnology, FORTH-HELLAS, Crete, Greece - 4Department of Internal Medicine, University Hospital of Heraklion, Crete, Greece - 5Department of Clinical Chemistry, School of Medicine, University of Crete, Crete, Greece
Referenza Journal of Renal Care 2014; 9999: 1–9
Contenuto

Objective: Several anthropometric, laboratory and bioelectrical impedance parameters of nutritional status and inflammation are often used as prognostic indices in patients on dialysis. Their longitudinal assessment is necessary for the estimation of their true prognostic value. We aim to estimate this prognostic value in better-nourished dialysis patients, which are commonly under-represented in pertinent studies.

Methods: The design is a prospective case series. Pertinent parameters were studied three times during a 20-month period in 47 haemodialysis (HD) and 27 peritoneal dialysis (PD) patients with a low malnutrition-inflammation score (MIS). Mortality rate was assessed three years after the initial evaluation. Correlation coefficients were calculated between mortality rate, the studied parameters and their alteration.

Results: Serum albumin of less than 40 g/l was strongly correlated with mortality risk. The alteration of studied parameters during a short period of time does not allow for long-term prediction of mortality risk.

Conclusion: Serum albumin had the strongest predictive value of all the pertinent parameters in the study. Thus, better conjugate clinical and laboratory measurements should be developed for patients on PD, as well as for those with a relatively low MIS.

Data 15.09.2014
 
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