Home / FlashMed

FlashMed

Titolo BIOIMPEDANCE SPECTROSCOPY FOR THE DETECTION OF FLUID OVERLOAD IN CHINESE PERITONEAL DIALYSIS PATIENTS
Autore Bonnie Ching-Ha Kwan, Cheuk-Chun Szeto, Kai-Ming Chow, Man-Ching Law, Mei Shan Cheng, Chi-Bon Leung, Wing-Fai Pang, Vickie Wai-Ki Kwong, and Philip Kam-Tao Li
Referenza Peritoneal Dialysis International 2013; doi: 10.3747/pdi.2013.00066
Contenuto

Background: Fluid overload probably contributes to the cardiovascular risk of peritoneal dialysis (PD) patients. We studied the relationship between over-hydration as determined by bioimpedance spectroscopy and dialysis adequacy, nutritional status, and arterial stiffness in Chinese PD patients.

Methods: We studied 122 asymptomatic prevalent PD patients: bioimpedance spectroscopy, arterial pulse wave velocity, dialysis adequacy and nutritional status were determined.

Results: Of the 122 patients, 88 (72.1%) had over-hydration of ≥ 1 L, while 25 (20.5%) were ≥ 5 L. Overhydration significantly correlated with total body water (r = 0.474, p < 0.001) and extracellular water (r = 0.755, p <0.001). Over-hydration was more severe in male and diabetic patients, and significantly correlated with Charlson’s comorbidity score, blood pressure, body mass index, body weight, peritoneal transport characteristics, and carotid-femoral pulse wave velocity. Over-hydration significantly correlated with Kt/V (r = -0.287, p = 0.016), serum albumin level (r = -0.465, p < 0.001) and malnutrition inflammation score (r = 0.410, p = 0.006), but not residual renal function.

Conclusion: Over-hydration is common in asymptomatic Chinese PD patients. The degree of over-hydration is particularly pronounced in patients who are inadequately dialyzed, have multiple comorbid conditions and low serum albumin levels. Over-hydration is associated with high blood pressure and arterial stiffness, and may contribute to the excessive risk of cardiovascular disease in this group of patients.

Data 03.09.2014
 
Maggiori informazioni   
Lista completa