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Titolo Assessment of Extracellular Fluid Volume and Fluid Status in Hemodialysis Patients: Current Status and Technical Advances
Autore Yanna Dou, Fansan Zhu, and Peter Kotanko - Renal Research Institute, New York, New York, Beth Israel Medical Center New York, New York, and Renal Division, Peking University First Hospital, Beijing, China
Referenza Seminars in Dialysis 20012; DOI: 10.1111/j.1525-139X.2012.01095.x

The assessment of extracellular fluid volume (ECV) and fluid status is both important and challenging in hemodialysis patients. Extracellular fluid is distributed in two major subcompartments: interstitial fluid and plasma. A variety of methods are used to assess the ECV, with tracer dilution techniques considered gold standard. However, ECV defined as the distribution space of bromide, sodium, chloride, and ferrocyanide appears to be larger than the distribution volume of inulin and sucrose, suggesting a partial distribution into the intracellular volume. Relative blood volume monitoring, measurement of inferior vena cava diameter by ultrasound and biochemical markers are indirect methods, which do not reflect the ECV and fluid status accurately. Bioimpedance spectroscopy (BIS) techniques enable assessment of ECVand intracellular volume. Currently, BIS appears to be the most practical method for assessing ECV volume and fluid status in dialysis patients.

Data 05.11.2012
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